Enable natural scrolling in Windows

1) Identify the mouse/touchpad information via Device Manager

2) regedit

3) Computer\HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Enum\HID

tip: On Windows 10, you can now copy and paste the path in the Registry's address bar to quickly jump to the key destination.

4) Expand the key (folder) that matches the VID ID of your mouse:

Computer\HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Enum\HID\VID_248A&PID_8368&MI_00&Col01\8&1f989acc&0&0000\Device Parameters

5) Double-click the FlipFlopWheel DWORD and set the value from 0 to 1

6) Reboot your PC

Enable natural scrolling in xfce4

- Run /usr/lib/gnome-settings-daemon/gnome-settings-daemon.
It can be enabled in Settings -> Session and Startup -> Autostart -> GNOME Settings Daemon

- In dconf-editor find touchpad.
It can be in org.gnome.settings-daemon.peripherals.touchpad or in org.gnome.desktop.peripherals.touchpad.
Enable natural-scroll option.

- Reboot

Note:
reverse scroll direction option in System Settings should be disabled in my case